ISOLASI FUNGI ENDOFIT PENGHASIL ANTIBIOTIKA PADA ALGA MERAH JENIS Gracilaria verrucosa SECARA KLT-BIOAUTOGRAFI
ABSTRACT: This research aimed
to determine the antibacterial fungi endofitic isolate of Gracilaria verrucosa
type Rhodophyta that antibiotic as potential by Bioautography-TLC Method. The
result of fungi endofitic isolate, obtained that 7 active isolates and purified
by quadrant method on potato dextrose agar medium obtained 5 active isolates
(isolate 1, 2, 3, 5, 6). The result of the screening of fungi endofitic isolate
by cakram method possessed that the biggest inhibitory zone is isolate 2 and
isolate 6 by 25 mm at Streptococcus mutans. The test results of fungi endofitic
isolate activity by Bioautography-TLC obtained Rf 0.07 0.23, 0.56, 0.78, 0.81
and 0.94 value actif inhibited Bacillus subtilis, Shigella disentry,
Streptococcus mutans and Eschericia coli. And the identification results of the
chemical component shown that the actif compound at isolate 2 and isolate 6
given result positif alkaloid.
Kata Kunci: Ethanol extract of
stem Phytocrene macrophylla Blume, agar diffusion, antibacterial
Penulis: Herwin
Kode Jurnal: jpfarmasidd180151
