Korelasi Kajian Fisikokimia Ekstrak Klika Faloak (Sterculia populifolia DC.) Menggunakan Variasi Pelarut Terhadap Penghambatan Bakteri Patogen
ABSTRACT: Faloak (Sterculia
populifolia DC.) is one of species of sterculiaceae found inEast Nusa Tenggara
which has potential as a medicinal plant mainly as anantimicrobial. This study
aims to determine the correlation ofphysicochemical study of faloak bark
extracts with variation of solvents ininhibiting of pathogenic bacteria. The
sample was extracted by macerationmethod with different polarity level of
solvents i.e acetone, acetone 70%,water, ethanol 96%, ethanol 70% and ethanol
50%. The results of extractionthrough maceration indicate the difference of
yield recovery from each of theextraction solvents. The highest yield was
obtained from 70% ethanolextract, while the lowest yield of acetone extract.
The increase of solvent polarity in this study did not give effect to the
amount of recovery of yield. Itis also seen from the highest total phenolic
content obtained from 70%acetone extract while the lowest in aquadest extract.
The antibacterialactivity of faloak bark extract on Salmonella typhi was tested
using agardiffusion method with 1% of extract solution. Both of ethanol 96% andacetone
extracts did not show any inhibitory activity. The largest inhibitoryactivity
was demonstrated by 50% ethanol extract. The polarity level of theextract, the
level of total phenolic content and the magnitude of rendement did not show
correlation of increased inhibitory activity on Salmonella thypias well
Kata Kunci: Faloak (Sterculia populifolia DC), variasi pelarut,
antimikroba
Penulis: Reny Syahruni
Kode Jurnal: jpfarmasidd180209
