PEMANFAATAN JAMUR ENDOFIT DARI DAUN MURBEI (Morus alba L.) SEBAGAI ANTIBIOTIK
Abstrak: Endophytic fungi are
fungi colonize internally plant tissue, without giving detrimental effect to
the host plant. They act as symbiont, mediated plant resistance against biotic
stress i.e. pests and diasease and abiotic stress such as drought and extreme
of temperature. Endophytic fungi are one of the most creative groups of
secondary metabolite producers that play important biological roles for human
life. Fungi are among the most important groups of eukaryotic organisms that
are well known for producing many novel metabolites which are directly used as
drugs or function as lead structure for modification.
Mulberry (Morus alba L.) is one of the genus species known to have
secondary metabolite compound that can be used as an antioxidant,
antibacterial, antiviral, antidiabetic, antihypertensive, hypolipidemic, fever,
flu, cough, antiemetic and gastrointestinal disorders. This research aimed to
determine antibacterial activity of Mulberry Fungi from the leaves against the
bacteria Escherichia coli and Staphylococcus aureus. Isolation of endophytic
fungal carried by the direct isolation techniques. Isolates which produced as
much as 3 isolates the MUR1, MUR2 and MUR3. Further isolates fermented using
PDY medium and extracted using ethyl acetate. The ethyl acetate extract qualitative
test the activity against bacteria Escherechia coli and Staphylococcus aureus.
The result of the antibacteria activity, ethyl acetat extract from fermentation
medium PDY of Mulbery (Morus alba L.) inhibited growth of Escherechia coli and
Staphylococcus aureus at > 12 mm
Keywords: Endophytic fungi,
Mulberry (Morus alba L.), Antibiotic.
Penulis: Sukriani Kursia,
Alimuddin Ali, Fitriyanti Jumaetri Sami, Rabiatul Adhawiyah
Kode Jurnal: jpfarmasidd170398
