Pengaruh Ekstrak Etanol Daun Binahong (Anredera Cordifolia (Tenore) Steen) Terhadap Penyembuhan Luka Sayat Pada Tikus Putih Jantan
Abstrak: Wound healing is a
normal process as responds by the skin tissue injury. This research is purposed
to see the effects of ethanol extract in binahong leaf to healing the wound of male white rats. There
are rats which are divided into five treatment groups, group I (negative
control), group II is given providone iodine 10% (positive control), group III,
IV and V are given the extract of binahong leaf ointment consist of 5%, 10%,
15% for each. By making a wound on the back of the rats about 20 mm long and 2
mm deep. The ointment is applied based on the treatment for each group twice a
day during ten days, the lenght count every day by using caliper. The data is
analyzed by using two ways ANOVA and continued by Duncan Test. The result
showed that ethanol extract in binahong leaf can heal the wound in scale
concentration about 10%-15%, length of wound was decrease on seventh day. The
more extract concentration given, the more effect in wound healing
Kata Kunci: Binahong extract;
povidone iodine; rats
Penulis: Aried Eriadi, Helmi
Arifin, Zet Rizal, Barmitoni
Kode Jurnal: jpfarmasidd150614