Pengaruh Pemberian Ekstrak Etanol Daun Sisik Naga (Pyrrosia piloselloides (L.) M. G Price) Terhadap Waktu Pendarahan, Waktu Pembekuan Darah dan Jumlah Trombosit Mencit Putih Jantan
Abstrak: Research on the
effect of ethanol extract of leaf dragon scales (Pyrrosia piloselloides (L.) M.
G Price) against clotting time, bleeding time and the number of platelet cells
in mice white male. The parameters observed owere the bleeding time, clotting
time of blood by the method of the slide and the number of platelet cells by
direct calculation method. Animal experiment was divided into 5 groups:
negative control group, the dose of 100 mg/kg BW, a dose of 200 mg / kg BW, a
dose of 400 mg/kg BW, and by comparison of vitamin K at a dose of 0,026 mg / kg
orally. Effects were observed on day 7, 14 and 21. The study showed that
ethanol extract leaf dragon scales (Pyrrosia piloselloides (L.) M. G Price) can
shorten the bleeding time, shorten the clotting time of blood and increase the
number of cells platelet white male mice. A dose of 400 mg/kg BW has been
giving maximum effect in shorten bleeding time, shorten the clotting time of
blood and can increase the number of platelet cells in mice white male.
Kata Kunci: Bleeding Time;
Blood Clotting; Platelet; Ethanolic Extract Pyrrosia piloselloides
Penulis: Sri Oktavia, Helmi
Arifin, Eddy Duarto
Kode Jurnal: jpfarmasidd170361
