Sensitivity of Escherichia coli Bacteria Towards Antibiotics in Patient with Diabetic Foot Ulcer
Abstract: Chronic complication
of diabetes mellitus is diabetic foot ulcers. Diabetic foot ulcer can be
defined as an open wound in the feet which will become infected as the result
of high blood sugar levels that develops and become place of bacteria. One of
the bacteria in diabetic foot ulcer is Escherichia coli. Imprecise use of
antibiotics in the treatment of diabetic foot ulcers can cause antibiotic
resistance to bacteria. This study aims to determine antibiotic sensitivity of
Escherichia coli bacteria in diabetic
foot ulcer Wagner grade III and IV. Samples of diabetic foot ulcer swab's with
Wagner grade III and IV were taken as Consecutive sampling. Identification of
Escherichia coli bacteria is done by using a biochemical test and Gram stain
test. Antibiotic sensitivity test is conducted
by using Kirby Bauer's disc of diffusion method. Escherichia coli
bacteria that were tested are sensitive to
amikacine, gentamicine, ciprofloxacin, levofloxacine, ceftriaxone,
cefotaxime, imipenem and meropenem antibiotics but showed resistant to
cefadroxil.
Keywords: diabetic foot
ulcers; Escherichia coli; antibiotic sensitivity
Penulis: Rafika Sari, Pratiwi
Apridamayanti, Indira Diah Puspita
Kode Jurnal: jpfarmasidd180187