The Potential Use of Red Ginger (Zingiber officinale Roscoe) Dregs as Analgesic
Abstrak: Red ginger (Zingiber
officinale Roscoe) had been used as excipient in jamu for most people in Indo-
nesia. Based on recent research, ethanol extract of red ginger had analgesics
activity. The purpose of this research to determine analgesic activity content
in water extract of the fresh and dry red ginger and ethanol extract of fresh
and dry of red ginger dregs. Fresh and dry of red ginger extracted using decoc-
tion method, and the dregs of fresh and dry red ginger extracted using
soxhletation method in ethanol 96% at 400C. Red ginger water extract and red
ginger dregs extract had been examined for analgesic by witkin method. The
results showed, fresh and dry red ginger water extract had analgesic activity
for 25 minutes but the activity reduced in 30 minutes. Fresh and dry red ginger
dregs ethanol extract still had analgesic activity until 30 minutes. TLC
chromatogram was sprayed with FeCl3 and formed two spots with grey colour for
both extracts. After sprayed with vanillin sulfate, it formed violet and blue
spots from both extracts. From the retention factor (Rf) , possibility shogaol
and gingerol contained in extract that have analgesic activity.
Key words: Analgesic, dregs,
phenolic, red ginger (Zingiber o cinale Roscoe), Witkin method
Penulis: Yessi Febriani, Hesti
Riasari, Wiwin Winingsih, Diah Lia Aulifa, Ayu Permatasari
Kode Jurnal: jpfarmasidd180235
