UJI AKTIVITAS ANTIDIARE EKSTRAK ETANOL 70% KULIT BUAH JENGKOL (Archidendron pauciflorum (Benth.) I.C.Nielsen) TERHADAP MENCIT JANTAN YANG DIINDUKSI OLEUM RICINI
Abstract: Plants that can be
used as a medicinal plant one of which is Jengkol (Archidendron pauciflorum
(Benth.) IC.Nielsen.). Seeds, bark and leaves jengkol contains saponins,
flavonoids and tannins. The purpose of this study was to test the antidiarrheal
activity of 70% ethanol extract of the fruit peel jengkol (Archidendron
pauciflorum (Benth.) ICNielsen) to male mice that includes a solution of
distilled water as a control, loperamide as a comparison, the ethanol extract
of the fruit peel jengkol as test material, and oleum ricini as inductors.
Research method used laboratory experiments. Data were analyzed by ANOVA
(Analysis of Variance) and continued with different test average – average Duncan
using SPSS (Statistical Product and Service Solutions). The results of that
study 70% ethanol extract of the fruit peel jengkol (Archidendron pauciflorum
(Benth.) IC Nielsen) provide nonspecific antidiarrheal activity. The content of
the metabolites were present in 70% ethanol extract of the fruit peel jengkol
(Archidendron pauciflorum (Benth.) IC Nielsen) which provides non-specific
activity as antidiarrheal are tannins, flavonoids and steroids. Ethanol Extract
Fruit Leather Jengkol 1.2 mg / g has a stronger effect in reducing diarrhea and
provide optimum activity as nonspecific antidiarrheal.
Keywords: Pithecellobium lobatum Benth, antidiarrheal, Oleum ricini
Penulis: Mohammad Rizal,
Yusransyah, Sofi Nurmay Stiani
Kode Jurnal: jpfarmasidd160455
