UJI AKTIVITAS EKSTRAK ETANOL DAUN ALPUKAT (Persea americana Mill.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA PUNGGUNG MENCIT PUTIH JANTAN (Mus musculus)
Abstract: Activity Assay of
avocado leaf (Persea americana Mill.) ethanol extract on burn healing at back
skin of white male mice (Mus musculus) aims to determine the best concentration
of avocado leaf ethanol extract to healing burn on back skin of mice. Extract
of avocado leaf obtained by maceration method using ethanol 70%. Burn made by
soldering iron modified with square plate (size 1 x 1 cm2), during 2 seconds
contact at the skin and make the skin formed blister. Observation of the burn
area was doing daily for 14 days, and also the treatment with the 3
concentrations extract variation (20%,35%, and 50%), negative control and
positive control. Result of research show that all avocado leaf ethanol extract
in concentrations 20%, 35% and 50% have good activity in burn healing, from
first day until 14th day they showed percentage of burn recovering successively
equal to 86%, 88% and 90%. Negative control showed that process healing of burn
was very tardy, only has percentage of burn recovering equal to 32,67% on 14th
day, while positive control showed 100% burn healing on 11st day. The best
concentration of avocado leaf ethanol
extract on healing burn is 50% with 90% burn healing
Keywords: Persea americana Mill, burn healing, back skin of mice
Penulis: Triswanto Sentat, Rizki
Permatasari
Kode Jurnal: jpfarmasidd150528
