Uji Efek Immunomodulator Dari Ekstrak Daun Manggis (Garcinia mangostana L.) Dengan Metode Carbon Clearence dan Menghitung Jumlah Sel Leukosit Pada Mencit Putih Jantan
Abstrak: The research of
immunomodulatory effect from the mangosteen (Garcinia mangostana) leaves
ethanol extract with a carbon clearance method and the counting of leukocytes
cell amount in male white mice. Has been done the ethanol extract of mangosteen
(Garcinia mangostana) leaves is given to every mouse during six days with a 100
mg/kg BW, 300 mg/kg BW, and 900 mg/kg BW dose. In the seventh day, it has been
decided a phagocyte index and the percentage amount of neutrophils, eusinofil,
basophile, monocytes and lymphocytes. The result of the research is showing a
given ethanol extract of mangosteen (Garcinia mangostana) leaves at the 100
mg/kg BW, 300 mg/kg BW, and 900 mg/kg BW dose, it can increase a phagocytes
index that is >1and increase the
amount of leukocytes cell that the extract has a characteristic of
immunostimulatory.
Kata Kunci: Mangosteen;
Garcinia mangostana L; Imunomodulator; Carbon Clearence
Penulis: Yufri Aldi, Sri
Oktavia, Sirda Yenni
Kode Jurnal: jpfarmasidd160610
