Uji Efektivitas Antihiperglikemia Kombinasi Jus Pare (Momordica charantia L) dan Jus Tomat (Solanum lycopersicum L) pada Tikus Wistar Jantan dengan Metode Toleransi Glukosa
Abstract: Diabetes melitus
(DM) is a metabolic disorder condition characterized by hyperglycemia. Bitter
melon (Momordica charantia L) and tomato (Solanum lycopersicum L) are plant
that have actvity antihiperglicemic actvity that contain triterpenoid,
flavonoid, alkaloid, and saponin. The purpose of this study was to determine
the effect of the combination antihiperglicemic bitter melon juice and tomato
juice on male Wistar rats that was induced sucrose. Animals were divided into 6
groups. Blood glucose levels was measured at 30th, 60th, 90th and 120th minutes
with enzymatic method using a glucometer. Data were analyzed statistically by Kruskal-Wallis
and Mann-Whitney with a 95% confidence
level. The research showed a blood glucose level of negative group differ
significantly from the other group (P>0.05 ) and did not differ
significantly with group 6 (P>0.05). Group 5 (bitter melon juice 17.4 g/KgBW
and tomato juice 16.8 g/KgBW) has a significant difference (P<0.05) with
other groups and more effectively lowering blood glucose levels from minute
90th to minute 120th. Group 5 has the lowering effect of blood glucose levels
than single juice.
Keywords: diabetes; jus; pare;
tomat; toleransi glukosa; diabetes; juice; Momordica charantia L; Solanum
lycopersicum L; glucose tolerance
Penulis: Wulandari
Kode Jurnal: jpfarmasidd160715
